Eptifibatide for the Treatment of HeartMate II Left Ventricular Assist Device Thrombosis

Eptifibatide for the treatment of HeartMate II left ventricular assist device thrombosis.

L eft ventricular assist device (LVAD) thrombosis is a life-threatening complication occurring in ≈6% of patients receiving a HeartMate II (HMII) LVAD (Thoratec Corp, Pleasanton, CA) within 24 months after implantation. 1 Prophylactic therapy with aspirin and warfarin to an international normalized ratio (INR) of 1.5 to 2.5 is recommended to prevent LVAD thrombosis in most HMII recipients. 2 Fo...

Surgical technique influences HeartMate II left ventricular assist device thrombosis.

BACKGROUND Thrombosis of the HeartMate II (HM2 [Thoratec Corporation, Pleasanton, CA]) is a potentially devastating complication. While attention has been focused on anticoagulation strategies to prevent this complication, the impact of surgical technique has not been assessed. METHODS Patients undergoing HM2 implantation at two institutions were reviewed. Pump thrombosis (PT) was defined as ...

Migration of a HeartMate II left ventricular assist device.

HeartMate II left ventricular assist device; early European experience.

OBJECTIVE The novel axial flow left ventricular assist device HeartMate II was introduced into clinical practice in Europe as part of the pilot study and after CE approval in November 2005. In order to get an overview of the use and performance of the device in Europe a group of investigators was founded to compare the initial results. METHODS In a retrospective analysis of the first 101 cons...

Comparison of left ventricular geometry after HeartMate II and HeartWare left ventricular assist device implantation

BACKGROUND HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry. METHODS The left ventricular end diastolic (LVEDD) and end systolic (LVESD) diameters were compared betwee...